Background Persistence of myofibroblasts is believed to contribute to the development of fibrosis in idiopathic pulmonary fibrosis (IPF). Transforming growth factor β1 (TGFβ1) irreversibly converts ...
5 Department of Respiratory Medicine, The Children's Hospital at Westmead, Australia 6 The Children's Hospital at Westmead Clinical School, Discipline of Paediatrics and Child Health, Faculty of ...
Correspondence to Professor Wim Janssens, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium; wim.janssens{at}uzleuven.be Rationale Estimating the ...
a Department of Physiology and Pharmacology, Karolinska Institute, 171 77 Stockholm, Sweden, b Department of Anesthesiology and Intensive Care, Karolinska Hospital 171 76 Stockholm, Sweden Dr J O N ...
Background Exercise and traditional airway clearance techniques (ACTs) are both routinely recommended for people with cystic fibrosis (CF), with some people using exercise as a substitute for ...
Department of Respiratory Medicine, St James’s University Hospital, Leeds LS9 7TF, UK Correspondence to: Dr P K Plant, Department of Respiratory Medicine, Level 7, Gledhow Wing, St James’s University ...
1 School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK 2 Directorate of Medicine, Norfolk and Norwich University Hospital, Norwich, Norfolk, UK ...
2 Guy's and St Thomas' Foundation NHS Trust, London, UK 3 Greenwich Primary Care Trust, London, UK 4 Croydon Primary Care Trust, London, UK Background The COPD (chronic obstructive pulmonary disease) ...
Background Despite progress in TB control in low-burden countries like England and Wales, there are still diagnostic delays. Molecular testing and/or whole-genome sequencing (WGS) provide more rapid ...
Background Chronic Obstructive Pulmonary Disease (COPD) is associated with persistent airway inflammation, which may be driven by an imbalance between pro-inflammatory macrophages and dysfunctional ...
Various forms of diffuse parenchymal lung disease have been proposed as potential consequences of severe COVID‑19. We describe the clinical, radiological and histological findings of patients with ...
Familial spontaneous pneumothorax (FSP) accounts for 10% of primary spontaneous pneumothoraces. Appropriate investigation of FSP enables early diagnosis of serious monogenic diseases and the practice ...
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