GEN - Genetic Engineering and Biotechnology News

CRISPR Screens Map Human T‑Cell Genes That Promote or Block HIV Infection

Genome‑wide CRISPR screens in primary human T cells reveal human genes that promote or block HIV infection, uncovering potent ...

Scientists map how HIV hijacks human cells—and how cells can fight back

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack ...
Medscape

Low CD4 Count Tied to Cervical Cancer Risk in HIV Infection

Among women with HIV infection, both lower CD4 counts and higher HIV RNA viral load were associated with higher incidence rates of moderate and severe cervical dysplasia, carcinoma in situ, and ...

Robin Weiss, virologist whose research on HIV was a crucial step in the race to design a vaccine

Robin Weiss, who has died aged 86, was a virologist who in 1984 led a team which identified CD4, a protein found on the ...
Medscape

HIV/TB Coinfection + Low CD4-Cell Count = Start ART Sooner Rather Than Later

The results of three randomized, controlled trials (SAPiT, STRIDE, and CAMELIA) demonstrate that, for coinfected patients with advanced immunosuppression, the survival benefit of starting ART within ...
The American Journal of Managed Care

CD4/CD8 Ratio a Useful Predictor of Mortality in Patients Living With HIV

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

HIV treatment reduces accelerated biological aging by nearly four years, landmark study shows

A major study presented at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ...