Brain tissue is an optical mess. Water, lipids, and tangled cellular membranes all bend light in different directions. If ...

The iSFR model enables accurate non-contact tissue analysis, achieving a 6.2% prediction error and overcoming limitations of ...

Tissue optical clearing is a fundamental technique that enhances light penetration deep into biological samples by reducing light scattering through refractive index homogenization. This process ...

It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole organs -- thanks to probe molecules that anchor fluorescent dyes within tissue as ...

Steps for deep-tissue 3D-imaging. Embryos or neonates fixed with 4% PFA were optically cleared with 60% TDE or tissue-clearing reagent CUBIC-L/R, and imaged using stereoscopic, confocal, or two-photon ...