An expert from CN Bio explores considerations when choosing an in vitro liver model . As the major drug metabolising organ, ...

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Modeling a genetic lipid disorder leads to the development of spontaneous fatty liver organoids. Lipids are depth-colored. [Delilah Hendriks & Benedetta Artegiani ...